Cholesterol

A waxy, fat-like substance that the body needs for cell membranes, steroid hormones, bile acids, and other biological functions.

The body produces cholesterol, mainly in the liver, and also obtains some from food. Because cholesterol does not dissolve freely in blood, it is transported in particles called lipoproteins.

Different lipoproteins have different relationships with cardiovascular risk. Elevated levels of certain cholesterol-containing lipoproteins, particularly LDL cholesterol, can contribute to atherosclerotic plaque formation.

QUICK FACT

Cholesterol itself is not inherently harmful; the body requires it. The health concern depends largely on its amount, how it is transported, and the broader cardiovascular context.

COMMONLY CONFUSED WITH

Triglycerides: another type of blood lipid that stores energy; triglycerides and cholesterol are different substances.

SEE ALSO

Clinical & Educational Context

Discussed in Health Articles & Guides

Explore how "Cholesterol" is covered across our evidence-based editorial guides:

1 Article
The Hard Parts of Medicine

Polypharmacy: What Really Happens When You Take Multiple Medicines

Imagine opening a medicine cabinet and finding tablets for blood pressure, diabetes, and cholesterol; medicines for pain or stomach discomfort; a vitamin supplement recommended...