Fatigue

A state of persistent or overwhelming tiredness, reduced energy, or diminished capacity for physical or mental activity.

Fatigue can be physical, mental, or both. It may result from inadequate sleep, prolonged exertion, stress, illness, medications, nutritional deficiencies, or many other causes.

Unlike ordinary tiredness that improves with adequate rest, persistent or unexplained fatigue may indicate an underlying health problem and should be considered in the context of other symptoms.

QUICK FACT

Fatigue is not the same as simply feeling sleepy. A person can be fatigued while having difficulty sleeping or without actually feeling a strong need to sleep.

COMMONLY CONFUSED WITH

Sleepiness: Sleepiness is a tendency to fall asleep, whereas fatigue is primarily a lack of energy or ability to sustain activity.

SEE ALSO

Clinical & Educational Context

Discussed in Health Articles & Guides

Explore how "Fatigue" is covered across our evidence-based editorial guides:

3 Articles
The Hard Parts of Medicine

Do You Need Supplements? What Medical Research Says

Fatigue, for instance, may be associated with iron deficiency, but it can also result from sleep problems, thyroid disease, infections, depression, and many other...
The Hard Parts of Medicine

Polypharmacy: What Really Happens When You Take Multiple Medicines

New swelling, muscle weakness, or unusual fatigue.
Health in the Wild

Noise Pollution 101: Everything You Need to Know

WHO explains that this can result from temporary fatigue of the sensory cells, and hearing may improve as the cells recover.