Polypharmacy

Polypharmacy is the use of multiple medicines by one person, particularly when the number or combination of medicines increases the potential for harm, unnecessary treatment, or medication-related problems.

There is no single universally accepted number of medicines that automatically makes a person’s treatment polypharmacy. The term is often used when several medicines are taken concurrently, especially when some may be unnecessary, inappropriate, duplicated, or interacting.

Polypharmacy can be appropriate when multiple conditions require treatment. The concern arises when the overall medication regimen becomes unnecessarily complex or exposes a person to avoidable risks such as adverse effects, drug interactions, dosing errors, and poor adherence.

QUICK FACT

Polypharmacy does not simply mean “too many medicines.” A person can appropriately need several medicines, while even two medicines can create a clinically important interaction.

COMMONLY CONFUSED WITH

Multimorbidity: Multimorbidity means having multiple health conditions at the same time; polypharmacy refers to the use of multiple medicines.

SEE ALSO

Clinical & Educational Context

Discussed in Health Articles & Guides

Explore how "Polypharmacy" is covered across our evidence-based editorial guides:

2 Articles
The Hard Parts of Medicine

Polypharmacy: What Really Happens When You Take Multiple Medicines

Polypharmacy, the use of multiple medicines by one person is becoming increasingly common as people live longer and more people receive treatment for multiple...
Unstraight Lines

40 Pills a Day

About this Reflection 40 Pills a Day is a reflection on the human side of polypharmacy; the part that is easy to miss when...