Targeted Therapy

Treatment designed to act on a specific biological molecule, pathway, cell feature, or disease mechanism involved in a particular condition.

Targeted therapy is particularly important in cancer treatment, where medicines may be designed to interfere with molecular abnormalities that help cancer cells grow, divide, survive, or spread. Examples include medicines that target specific receptors, enzymes, or signaling pathways.

Because targeted therapies act on particular biological features, they may affect normal cells less broadly than some traditional treatments. However, they are not free of side effects, and their effectiveness depends on whether the relevant target is present and remains important to the disease.

COMMONLY CONFUSED WITH

  • Chemotherapy: generally refers to medicines that kill or inhibit rapidly dividing cells without necessarily targeting a specific molecular abnormality.
  • Immunotherapy: works by modifying or harnessing the immune system, although some treatments can overlap conceptually with targeted therapy.

SEE ALSO

Clinical & Educational Context

Discussed in Health Articles & Guides

Explore how "Targeted Therapy" is covered across our evidence-based editorial guides:

1 Article
The Hard Parts of Medicine

Polypharmacy: What Really Happens When You Take Multiple Medicines

Polypharmacy, the use of multiple medicines by one person is becoming increasingly common as people live longer and more people...