Immune System

The interconnected network of cells, tissues, organs, and biological processes that protects the body from infectious agents, abnormal cells, and other potentially harmful substances.

The immune system includes components such as white blood cells, antibodies, lymphatic tissues, bone marrow, the thymus, lymph nodes, and the spleen. It uses both innate and adaptive immune defenses.

The immune system must distinguish harmful or abnormal targets from the body’s own healthy tissues. When immune activity is inadequate, excessive, or misdirected, disease can result.

QUICK FACT

The immune system does not only fight infections; it also helps identify and remove damaged or abnormal cells.

COMMONLY CONFUSED WITH

Immune response: the specific coordinated reaction produced by the immune system; the immune system is the broader network that produces those responses.

SEE ALSO

Clinical & Educational Context

Discussed in Health Articles & Guides

Explore how "Immune System" is covered across our evidence-based editorial guides:

1 Article
The Hard Parts of Medicine

Polypharmacy: What Really Happens When You Take Multiple Medicines

Polypharmacy, the use of multiple medicines by one person is becoming increasingly common as people live longer and more people...