Infection

The entry, establishment, and multiplication or persistence of an infectious agent in a host.

An infection occurs when an infectious agent such as a bacterium, virus, fungus, or parasite enters a host and successfully establishes itself. The body may eliminate the agent without causing noticeable illness, or the infection may lead to an infectious disease with symptoms, signs, or tissue damage.

Infection does not necessarily mean that a person is visibly sick or has symptoms. Some infections are asymptomatic, while others can cause severe disease. Infections may be acquired through direct contact, respiratory droplets or aerosols, contaminated food or water, sexual contact, vectors, or other routes.

COMMONLY CONFUSED WITH

  • Inflammation: a biological response that can result from infection but can also occur without infection.
  • Infectious disease: disease caused by an infection; an infection does not always produce disease.
  • Contamination: the unwanted presence of an infectious agent or other substance where it does not belong; contamination does not necessarily mean infection has occurred.

SEE ALSO

Clinical & Educational Context

Discussed in Health Articles & Guides

Explore how "Infection" is covered across our evidence-based editorial guides:

5 Articles
Unstraight Lines

Kill Me a Little, Kill It More

From medicines that fight infections to chemicals used to control harmful organisms, the reflection considers the delicate balance between destroying a threat and protecting...
Medicine without Jargon

The Best Birthing Position: What Current Evidence Says

Without prompt treatment, obstructed labor can lead to: Uterine rupture Severe infection Postpartum hemorrhage Injury to the birth canal Oxygen deprivation in the baby...
The Hard Parts of Medicine

Do You Need Supplements? What Medical Research Says

Fatigue, for instance, may be associated with iron deficiency, but it can also result from sleep problems, thyroid disease, infections, depression, and many other...
The Hard Parts of Medicine

Polypharmacy: What Really Happens When You Take Multiple Medicines

Tuberculosis: Drug-susceptible tuberculosis is treated with a combination regimen designed to treat the infection effectively and help prevent the development of resistance.
Cases & Narratives

His Last Malaria: A Case of Suspected Fake Medicines

A medicine that is substandard or falsified can therefore do more than fail to treat the infection; it can contribute to lost time while...