Allergy

An immune system reaction to a substance that is normally harmless to most people.

An allergy occurs when the immune system recognizes a normally harmless substance, such as pollen, certain foods, medications, insect venom, or animal proteins, as a threat and mounts an inappropriate or exaggerated response.

Allergic reactions range from mild symptoms such as sneezing or itching to potentially life-threatening anaphylaxis. The specific immune mechanism varies between types of allergic reactions.

COMMONLY CONFUSED WITH

  • Intolerance: an adverse reaction to a substance that does not involve the same type of immune response as an allergy.
  • Hypersensitivity: a broader term for an exaggerated or inappropriate immune response; allergy is one type of hypersensitivity.

SEE ALSO

Clinical & Educational Context

Discussed in Health Articles & Guides

Explore how "Allergy" is covered across our evidence-based editorial guides:

1 Article
The Hard Parts of Medicine

Polypharmacy: What Really Happens When You Take Multiple Medicines

Polypharmacy, the use of multiple medicines by one person is becoming increasingly common as people live longer and more people...