Fever

A regulated increase in body temperature caused by the body’s physiological response to a disease or other trigger.

Fever commonly occurs when the immune system responds to an infection or inflammation and raises the body’s temperature set point. The brain’s hypothalamus coordinates this change, which can produce chills, shivering, and later sweating as the temperature changes.

Fever is a sign, not a disease itself. Its significance depends on factors such as the person’s age, underlying health, temperature, duration, associated symptoms, and cause.

QUICK FACT

Fever and overheating are not the same. Fever involves a regulated change in the body’s temperature set point, whereas overheating can occur when the body gains or produces more heat than it can dissipate.

COMMONLY CONFUSED WITH

Hyperthermia: Fever involves a regulated increase in temperature; hyperthermia occurs when body temperature rises without an appropriate change in the body’s temperature set point.

SEE ALSO

Clinical & Educational Context

Discussed in Health Articles & Guides

Explore how "Fever" is covered across our evidence-based editorial guides:

3 Articles
Unstraight Lines

Kill Me a Little, Kill It More

Let the invader fall before the fortress does; let the fever lose its fire before my strength gives way.
The Hard Parts of Medicine

Polypharmacy: What Really Happens When You Take Multiple Medicines

For instance, some cold and flu products contain an ingredient that is also sold separately as a pain reliever or fever reducer.
Cases & Narratives

His Last Malaria: A Case of Suspected Fake Medicines

From inside the experience of persistent fever and uncertainty, however, it can feel like taking responsibility.