Liver

A large organ in the upper right part of the abdomen that performs essential functions in metabolism, detoxification, digestion, nutrient storage, and processing of substances in the blood.

The liver produces bile, processes nutrients absorbed from the intestine, stores substances such as glycogen and certain vitamins, modifies and helps eliminate many drugs and toxins, and produces important blood proteins. It also processes bilirubin produced from the breakdown of hemoglobin. Because the liver performs many different functions, liver disease can affect multiple body systems.

QUICK FACT

The liver has a remarkable capacity to regenerate after certain types of injury or partial removal, although severe or chronic damage can impair this ability.

COMMONLY CONFUSED WITH

Gallbladder: the gallbladder stores and concentrates bile produced by the liver; it does not produce bile.

SEE ALSO

Clinical & Educational Context

Discussed in Health Articles & Guides

Explore how "Liver" is covered across our evidence-based editorial guides:

4 Articles
The Hard Parts of Medicine

Do You Need Supplements? What Medical Research Says

Having kidney or liver disease or another condition that affects nutrient handling.
The Hard Parts of Medicine

Polypharmacy: What Really Happens When You Take Multiple Medicines

However, changes in kidney function, liver function, body composition, mobility, and sensitivity to certain drugs can alter how a person responds to treatment.
Medicine without Jargon

The Best Birthing Position: What Current Evidence Says

A woman in labor is ready to push. One nurse encourages her to lie back, while another suggests turning onto...
Unstraight Lines

40 Pills a Day

A medicine that was appropriate years ago may need its dose adjusted, its risks reconsidered, or its continued use reassessed as diseases, kidney or...